Neighborhood 48H guide
Signoria & Ponte Vecchio: Where to Stay & What to Do in 48 Hours
The Uffizi, Palazzo Vecchio and the old bridge.

South of the Duomo, Piazza della Signoria opens onto Palazzo Vecchio and the Uffizi, which runs down to the Arno and the Ponte Vecchio. Palazzo Strozzi’s exhibitions and the shops of Via de’ Tornabuoni are a few minutes west.
Photo gallery

Photo: Ingo Mehling · CC BY-SA 4.0 · Wikimedia Commons 
Photo: Armin Kleiner · CC BY-SA 4.0 · Wikimedia Commons 
Photo: Txllxt TxllxT · CC BY-SA 4.0 · Wikimedia Commons 
Photo: John Samuel · CC BY-SA 4.0 · Wikimedia Commons
Why stay here
The great museums and the river at your door.
Who it's for: Art lovers and first-timers.
Pros
- Museums
- River views
- Central
Cons
- Very crowded
- Pricey
- Touristy eats
48H by the Signoria
Gallery, palace, exhibitions.
08:15 – Uffizi Gallery
Botticelli, Leonardo and Caravaggio; book ahead.
14:00 – Palazzo Vecchio
State rooms and the tower.
17:00 – Palazzo Strozzi
The current exhibition.
Named recommendations
Real places with links to their official site or a Maps place page. We do not invent hours, prices, or ratings.
See / do

See / do
Uffizi Gallery
Piazzale degli Uffizi
Italy’s great Renaissance collection, from Botticelli’s Birth of Venus on.
Photo: Armin Kleiner · CC BY-SA 4.0 · Wikimedia Commons Official site / map →
See / do
Palazzo Vecchio
Piazza della Signoria
The town hall on Piazza della Signoria, with frescoed state rooms and a tower.
Photo: Txllxt TxllxT · CC BY-SA 4.0 · Wikimedia Commons Official site / map →
See / do
Palazzo Strozzi
Piazza degli Strozzi
Renaissance palace hosting major art exhibitions.
Photo: John Samuel · CC BY-SA 4.0 · Wikimedia Commons Official site / map →See / do
Museo Galileo
Piazza dei Giudici 1
Science museum with Galileo’s own telescopes, by the Uffizi.
Official site / map →
Where to stay
Specific named properties—not vague city-wide searches. Expedia stays use tracked Creator links; others open the hotel's official site.
Roam48 may earn a commission when you book a stay through Expedia or Vrbo links on this page, at no extra cost to you. All commercial stay links use rel="sponsored nofollow".
Hotel · Expedia
Portrait Firenze - Lungarno Collection
Ponte Vecchio
Five-star hotel overlooking the Ponte Vecchio.
Check rates on Expedia →Hotel · Expedia
Gallery Hotel Art - Lungarno Collection
Ponte Vecchio
Art-filled boutique hotel steps from the Ponte Vecchio.
Check rates on Expedia →
Vacation rentals
Prefer an apartment or whole home in this neighborhood? Browse Vrbo listings for Signoria & Ponte Vecchio.
Since 1 January 2025, every Italian short-term and tourist rental must have a national identification code (CIN), shown in every online listing and outside the building. Hosts face fines of €800–8,000 for having no CIN and €500–5,000 for not displaying it. Before booking on Vrbo, check that the listing shows a CIN.
Browse vacation rentals in Signoria & Ponte Vecchio on Vrbo →Other ways to spend 48 hours in Florence
- Duomo — Brunelleschi’s dome and the Bargello.
- Santa Croce — Michelangelo’s tomb and a collector’s palace.
- Sant’Ambrogio — The Synagogue and Michelangelo’s house.
- Oltrarno — Pitti Palace, Boboli and Santo Spirito.
- Santa Maria Novella — The marble basilica and the station quarter.
- San Lorenzo — The central market and the Medici.
- San Marco & Santissima Annunziata — Michelangelo’s David and Brunelleschi’s loggia.